
Safe & Simple Withdrawal Relief to start your recovery
OpiEase is a small, wearable prescription medical device used as an aid to reduce symptoms of opioid withdrawal. It is designed to be comfortably worn on one ear for five days (120 hours) of continuous use. OpiEase is prescribed and applied by a qualified healthcare professional. Clinical studies have shown rapid and meaningful reductions in withdrawal symptoms. OpiEase does not replace medical care.
Medication-free · Non-surgical · Clinician-applied

When withdrawal becomes the biggest barrier
Common experiences described by patients. OpiEase may offer an alternative worth discussing with your provider.
I feel restless and can't sit still.
My body aches everywhere and I can't think straight.
I want to get help, but I'm afraid of what I'll have to go through.
I tried before, but the discomfort was just too much.
Why standard treatments can fall short
The gaps patients and providers describe most often — friction points that delay or derail the start of treatment.
Persistent discomfort during the early phase
Incomplete or inconsistent symptom relief
Difficulty tolerating withdrawal symptoms long enough to begin further treatment
Anxiety and stress about starting the process
A different approach

Delivers gentle electrical signals through specific nerve branches in the outer ear, including the vagus nerve, that are connected to pathways involved in physical stress and discomfort responses
Medication-free and non-addictive — does not cause sedation
Non-surgical and minimally invasive — four tiny microneedles placed on the outer ear
Simple, brief in-office placement without anesthesia or sedation
What patients commonly report
Rapidly and significantly reduced withdrawal symptoms (often within 20-60 minutes)
Made the beginning of recovery treatment easier to tolerate
Helped patients transition into ongoing care and treatment
Significantly decreased Clinical Opioid Withdrawal Scale (COWS) scores
Adrian Miranda & Arturo Taca (2018). The American Journal of Drug and Alcohol Abuse, 44:1, 56-63.
Individual results may vary
What to expect
Evaluation
A healthcare professional determines whether OpiEase is appropriate.
Placement
The device is applied through a brief, in-office placement process.
Continuous wear (5 days)
The device is worn continuously on one ear for up to 120 hours while continuing your treatment plan.
Removal & follow-up
The device is removed and care continues as directed by the clinician.
- 01Class II FDA-cleared medical device
- 02No serious adverse events or complications reported in clinical studies
- 03Reported side effects were rare, generally mild and temporary
- 04OpiEase is not MRI-compatible and is not recommended for use during pregnancy or in patients with certain implanted electrical devices unless cleared by a specialist
- 05Appropriateness for treatment is determined by a licensed healthcare provider
Questions about OpiEase
OpiEase is a prescription medical device. This webpage is for informational purposes only and does not provide medical advice. Patients should consult a licensed healthcare provider to determine whether OpiEase is appropriate for them. Individual results may vary. Distributed by MAI Medical USA Inc.
Ready to explore OpiEase?
Find a trained provider near you, or learn how to offer OpiEase in your practice.